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Cd84tm1Pls
Targeted Allele Detail
Nomenclature
Symbol: Cd84tm1Pls
Name: CD84 antigen; targeted mutation 1, Pamela L Schwartzberg
MGI ID: MGI:4438772
Gene: Cd84  Location: Chr1:171839697-171890718 bp, + strand  Genetic Position: Chr1, 79.54 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:157915
Parent Cell Line:  Other (see notes) (ES Cell)
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe second exon was replaced by two stops codons and a neo cassette by homologous recombination. Lack of expression was verified by flow cytometry. (J:157915)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cd84 Mutation:  14 strains or lines available
Notes
ES cell line = HGTC-8.

References
Original:  J:157915 Cannons JL, et al., Optimal germinal center responses require a multistage T cell:B cell adhesion process involving integrins, SLAM-associated protein, and CD84. Immunity. 2010 Feb 26;32(2):253-65
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
01/20/2015
MGI 5.21
The Jackson Laboratory