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Kdm3atm1.1Jsak
Targeted Allele Detail
Nomenclature
Symbol: Kdm3atm1.1Jsak
Name: lysine (K)-specific demethylase 3A; targeted mutation 1.1, Juro Sakai
MGI ID: MGI:4438720
Synonyms: JHDM2adelta
Gene: Kdm3a  Location: Chr6:71588972-71632990 bp, - strand  Genetic Position: Chr6, 32.18 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:158258
Parent Cell Line:  TT2 (ES Cell)
Strain of Origin:  (C57BL/6NCrlj x CBA/JNCrlj)F1
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsCre mediated recombination removed the cDNA corresponding to the genomic sequence of exon 20 through the coding region of exon 25 and a neo cassette. The absence of fully length protein expression was confirmed by western blot analysis on embryonic stem cell extracts. (J:158258)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Kdm3a Mutation:  55 strains or lines available
References
Original:  J:158258 Inagaki T, et al., Obesity and metabolic syndrome in histone demethylase JHDM2a-deficient mice. Genes Cells. 2009 Aug;14(8):991-1001
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/20/2017
MGI 6.10
The Jackson Laboratory