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Prpf31tm1.1Bha
Targeted Allele Detail
Nomenclature
Symbol: Prpf31tm1.1Bha
Name: pre-mRNA processing factor 31; targeted mutation 1.1, Shoumo Bhattacharya
MGI ID: MGI:4438621
Gene: Prpf31  Location: Chr7:3629985-3642486 bp, + strand  Genetic Position: Chr7, 2.09 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:158261
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S2/SvPas
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExon 7 was removed by cre mediated recombination resulting in a premature stop codon at position 186. (J:158261)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 3 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Prpf31 Mutation:  17 strains or lines available
References
Original:  J:158261 Bujakowska K, et al., Study of gene-targeted mouse models of splicing factor gene Prpf31 implicated in human autosomal dominant retinitis pigmentosa (RP). Invest Ophthalmol Vis Sci. 2009 Dec;50(12):5927-33
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/11/2018
MGI 6.12
The Jackson Laboratory