About   Help   FAQ
Gdf11tm2.2Sjl
Targeted Allele Detail
Nomenclature
Symbol: Gdf11tm2.2Sjl
Name: growth differentiation factor 11; targeted mutation 2.2, Sejin Lee
MGI ID: MGI:4438484
Synonyms: Gdf11delta2-3
Gene: Gdf11  Location: Chr10:128882295-128891718 bp, - strand  Genetic Position: Chr10, 77.18 cM, cytoband D3
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:158173
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsCre mediated recombination removed exons 2 and 3. This deletion is expected to remove the biologically active carboxy-terminal domain. (J:158173)
Generation of the Gdf11tm2.1Sjl and Gdf11tm2.2Sjl alleles
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gdf11 Mutation:  8 strains or lines available
References
Original:  J:158173 McPherron AC, et al., Redundancy of myostatin and growth/differentiation factor 11 function. BMC Dev Biol. 2009;9:24
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
02/23/2021
MGI 6.16
The Jackson Laboratory