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Tg(Pkd1)26Mtru
Transgene Detail
Nomenclature
Symbol: Tg(Pkd1)26Mtru
Name: transgene insertion 26, Marie Trudel
MGI ID: MGI:4437718
Synonyms: Pkd1TAG
Transgene: Tg(Pkd1)26Mtru  Location: unknown  
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(Pkd1)26Mtru expresses 1 gene
 
Mutation detailsA BAC was modifed to insert a silent mutation in exon 10 to act as a tag (G -> A). A second modification removed 34.5 kb of the Tsc2 gene from the BAC. Three lines were created (lines 6, 18, and 26) with 2 to 15 copies of the transgene (2, 6, and 15, respectively). (J:157952)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 21 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:157952 Kurbegovic A, et al., Pkd1 transgenic mice: adult model of polycystic kidney disease with extrarenal and renal phenotypes. Hum Mol Genet. 2010 Apr 1;19(7):1174-89
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
08/13/2019
MGI 6.14
The Jackson Laboratory