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Targeted Allele Detail
Symbol: Samsn1tm1Xyw
Name: SAM domain, SH3 domain and nuclear localization signals, 1; targeted mutation 1, Xiao-Yan Wen
MGI ID: MGI:4437672
Synonyms: Hacs1-
Gene: Samsn1  Location: Chr16:75858793-76022270 bp, - strand  Genetic Position: Chr16, 43.36 cM
Germline Transmission:  Earliest citation of germline transmission: J:158032
Parent Cell Line:  E14K (ES Cell)
Strain of Origin:  129P2/OlaHsd
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsGenomic sequence spanning part of exon 4 through part of exon 6 was replaced with a neo cassette. The absence of protein expression was confirmed by western blot analysis on IL4-stimulated splenic B cell extracts. (J:158032)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Samsn1 Mutation:  11 strains or lines available
Original:  J:158032 Wang D, et al., Enhanced adaptive immunity in mice lacking the immunoinhibitory adaptor Hacs1. FASEB J. 2010 Mar;24(3):947-56
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.11
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