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Il10ratm1.2Jack
Targeted Allele Detail
Nomenclature
Symbol: Il10ratm1.2Jack
Name: interleukin 10 receptor, alpha; targeted mutation 1.2, Robert S Jack
MGI ID: MGI:4437318
Synonyms: Il10R-
Gene: Il10ra  Location: Chr9:45253837-45269149 bp, - strand  Genetic Position: Chr9, 24.84 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:157787
Parent Cell Line:  E14.1 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    Cre mediated recombination removed exon 1 and the neo cassette. (J:157787)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Il10ra Mutation:  14 strains or lines available
References
Original:  J:157787 Pils MC, et al., Monocytes/macrophages and/or neutrophils are the target of IL-10 in the LPS endotoxemia model. Eur J Immunol. 2010 Feb;40(2):443-8
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/10/2017
MGI 6.10
The Jackson Laboratory