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Targeted Allele Detail
Symbol: Kcnu1tm1Cmsa
Name: potassium channel, subfamily U, member 1; targeted mutation 1, Celia M Santi
MGI ID: MGI:4437059
Synonyms: SLO3-
Gene: Kcnu1  Location: Chr8:25849623-25937939 bp, + strand  Genetic Position: Chr8, 14.17 cM, cytoband A3
Germline Transmission:  Earliest citation of germline transmission: J:157522
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
Mutation detailsThe mutation was generated by removal of the first two coding exons which includes the initiation codon and DNA sequence encoding the first and part of the second membrane spanning domains. The absence of the protein expression was confirmed by Western blot analysis of testes samples. (J:157522)
View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Kcnu1 Mutation:  36 strains or lines available
Original:  J:157522 Santi CM, et al., The SLO3 sperm-specific potassium channel plays a vital role in male fertility. FEBS Lett. 2010 Mar 5;584(5):1041-6
All:  3 reference(s)

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.11
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