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Targeted Allele Detail
Symbol: Nr4a2tm1.1Pcn
Name: nuclear receptor subfamily 4, group A, member 2; targeted mutation 1.1, Pierre Chambon
MGI ID: MGI:4437024
Synonyms: Nr4a2tm2.1Tpe, Nurr1L2
Gene: Nr4a2  Location: Chr2:57106830-57124003 bp, - strand  Genetic Position: Chr2, 31.66 cM
Germline Transmission:  Earliest citation of germline transmission: J:157098
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
Mutation detailsA loxP site was inserted upstream of exon 3 and a floxed neo cassette was inserted downstream of exon 3. Cre mediated recombination removed the neo cassette leaving exon 3 floxed. (J:157098)
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nr4a2 Mutation:  15 strains or lines available
Original:  J:157098 Kadkhodaei B, et al., Nurr1 is required for maintenance of maturing and adult midbrain dopamine neurons. J Neurosci. 2009 Dec 16;29(50):15923-32
All:  8 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.04
The Jackson Laboratory