About   Help   FAQ
Nr4a2tm1.1Pcn
Targeted Allele Detail
Nomenclature
Symbol: Nr4a2tm1.1Pcn
Name: nuclear receptor subfamily 4, group A, member 2; targeted mutation 1.1, Pierre Chambon
MGI ID: MGI:4437024
Synonyms: Nr4a2tm2.1Tpe, Nurr1L2
Gene: Nr4a2  Location: Chr2:57106830-57124003 bp, - strand  Genetic Position: Chr2, 31.66 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:157098
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA loxP site was inserted upstream of exon 3 and a floxed neo cassette was inserted downstream of exon 3. Cre mediated recombination removed the neo cassette leaving exon 3 floxed. (J:157098)
Phenotypes
Loading...
View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nr4a2 Mutation:  2 strains or lines available
References
Original:  J:157098 Kadkhodaei B, et al., Nurr1 is required for maintenance of maturing and adult midbrain dopamine neurons. J Neurosci. 2009 Dec 16;29(50):15923-32
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
04/07/2015
MGI 5.21
The Jackson Laboratory