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Vhltm1.1Wkr
Targeted Allele Detail
Nomenclature
Symbol: Vhltm1.1Wkr
Name: von Hippel-Lindau tumor suppressor; targeted mutation 1.1, WK Rathmell
MGI ID: MGI:4436910
Synonyms: Vhl2B
Gene: Vhl  Location: Chr6:113623959-113631633 bp, + strand  Genetic Position: Chr6, 52.81 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:157369
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted
Mutation:    Insertion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Vhl Mutation:  5 strains or lines available
References
Original:  J:157369 Lee CM, et al., VHL Type 2B gene mutation moderates HIF dosage in vitro and in vivo. Oncogene. 2009 Apr 9;28(14):1694-705
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory