About   Help   FAQ
Aldh2tm1a(EUCOMM)Wtsi
Targeted Allele Detail
Nomenclature
Symbol: Aldh2tm1a(EUCOMM)Wtsi
Name: aldehyde dehydrogenase 2, mitochondrial; targeted mutation 1a, Wellcome Trust Sanger Institute
MGI ID: MGI:4431566
Gene: Aldh2  Location: Chr5:121566027-121593824 bp, - strand  Genetic Position: Chr5, 61.86 cM, cytoband F-G1
Mutation
origin
Mutant Cell Lines:  EPD0089_4_A10, EPD0089_4_A11, EPD0089_4_B11, EPD0089_4_C10, EPD0089_4_C12, EPD0089_4_D10, EPD0089_4_D12, EPD0089_4_E12, EPD0089_4_F10, EPD0089_4_F11, EPD0089_4_F12, EPD0089_4_G10, EPD0089_4_H11, EPD0089_4_H12 (Wellcome Trust Sanger Institute)
Germline Transmission:  Earliest citation of germline transmission: J:165965
Parent Cell Line:  JM8.F6 (ES Cell)
Strain of Origin:  C57BL/6N
Project Collection: EUCOMM
Mutation
description
Allele Type:    Targeted (Conditional ready, Null/knockout, Reporter)
Mutation:    Insertion     Vector: L1L2_gt0
 
Mutation details
Phenotypes
Loading...
View phenotypes for all genotypes (concatenated display).
Disease models
Loading...
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 1 line available
Carrying any Aldh2 Mutation:  11 strains or lines available
Notes
Cell line EPD0089_4_F11 was successfully used to make chimeric mice. Germline transmission was accomplished. J:193232

References
Original:  J:155845 Wellcome Trust Sanger Institute, Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute. MGI Direct Data Submission. 2010;
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
10/08/2014
MGI 5.20
The Jackson Laboratory