About   Help   FAQ
Viptm1(cre)Zjh
Targeted Allele Detail
Nomenclature
Symbol: Viptm1(cre)Zjh
Name: vasoactive intestinal polypeptide; targeted mutation 1, Z Josh Huang
MGI ID: MGI:4431361
Synonyms: VIP-Cre, Vip-IRES-cre
Gene: Vip  Location: Chr10:5639218-5647617 bp, + strand  Genetic Position: Chr10, 1.97 cM, cytoband A1
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:151755
Parent Cell Line:  v6.5 (ES Cell)
Strain of Origin:  (C57BL/6 x 129S4/SvJae)F1
Project Collection: Neuroscience Blueprint cre
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutation:    Insertion
 
Mutation detailsA targeting vector was designed to insert an internal ribosome entry site (IRES), a cre recombinase sequence, an SV40 polyA signal, and an frt-flanked neo cassette into the 3' untranslated region (after the translational termination site) of the vasoactive intestinal polypeptide locus (Vip). This construct was electroporated into C57BL/6 x 129S4/SvJae hybrid embryonic stem (ES) cells. Chimeric mice were bred with Actin-FLPe mice (on a C57BL/6 congenic background) to generate the colony and remove the neo selection cassette. The FLPe transgene has been bred out of the line. (J:151755)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Vip     Summary of all recombinase alleles driven by Vip. Comparative matrix view of recombinase activities
 

Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Vip Mutation:  15 strains or lines available
References
Original:  J:151755 NIH Neuroscience Blueprint Cre Driver Network, Cre recombinase-expressing mice generated for the NIH Neuroscience Blueprint Cre Driver Network. MGI Direct Data Submission. 2009;
All:  89 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/26/2019
MGI 6.14
The Jackson Laboratory