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Tg(tetO-Notch4*)1Rwng
Transgene Detail
Nomenclature
Symbol: Tg(tetO-Notch4*)1Rwng
Name: transgene insertion 1, Rong Wang
MGI ID: MGI:4431198
Synonyms: TRE-int3
Transgene: Tg(tetO-Notch4*)1Rwng  Location: unknown  
Transgene
origin
Strain of Origin:  FVB/N
Transgene
description
Transgene Type:    Transgenic (Inducible, Inserted expressed sequence)
Mutation:    Insertion
 
Tg(tetO-Notch4*)1Rwng expresses 1 gene
 
Mutation detailsDNA encoding amino acids 1411-1964 of Notch4 was placed under the control of the tetracycline response element. (J:99859)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 13 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:99859 Carlson TR, et al., Endothelial expression of constitutively active Notch4 elicits reversible arteriovenous malformations in adult mice. Proc Natl Acad Sci U S A. 2005 Jul 12;102(28):9884-9
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/15/2018
MGI 6.12
The Jackson Laboratory