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Porcntm1.1Lcm
Targeted Allele Detail
Nomenclature
Symbol: Porcntm1.1Lcm
Name: porcupine homolog (Drosophila); targeted mutation 1.1, Lewis Murtaugh
MGI ID: MGI:4429133
Synonyms: Porcn-2lox, Porcn-lox
Gene: Porcn  Location: ChrX:8193848-8206525 bp, - strand  Genetic Position: ChrX, 3.7 cM
Focal dermal hypoplasia-like phenotypes in Porcntm1.1Lcm/Porcn+ Tg(Sox2-cre)1Amc/0 embryos

Show the 4 phenotype image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:173672
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation details
Derivation of Porcntm1.1Lcm mutant allele
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Porcn Mutation:  15 strains or lines available
References
Original:  J:173672 Barrott JJ, et al., Deletion of mouse Porcn blocks Wnt ligand secretion and reveals an ectodermal etiology of human focal dermal hypoplasia/Goltz syndrome. Proc Natl Acad Sci U S A. 2011 Jul 18;
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/16/2014
MGI 5.19
The Jackson Laboratory