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Stk3tm1Yy
Targeted Allele Detail
Nomenclature
Symbol: Stk3tm1Yy
Name: serine/threonine kinase 3; targeted mutation 1, Yingzi Yang
MGI ID: MGI:4422169
Synonyms: Mst2c, Mst2fl
Gene: Stk3  Location: Chr15:34875499-35155882 bp, - strand  Genetic Position: Chr15, 14.34 cM, cytoband B3.3
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:156541
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA loxP site was inserted upstream of exon 5 and an frt flanked neo cassette and second loxP site were inserted downstream of exon 6. (J:156541)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Stk3 Mutation:  12 strains or lines available
References
Original:  J:156541 Song H, et al., Mammalian Mst1 and Mst2 kinases play essential roles in organ size control and tumor suppression. Proc Natl Acad Sci U S A. 2010 Jan 26;107(4):1431-6
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
06/30/2020
MGI 6.15
The Jackson Laboratory