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Targeted Allele Detail
Symbol: Del(11Nmur2-Sparc)2Anjm
Name: deletion, Chr 11, Andrew N J McKenzie
MGI ID: MGI:4421680
Synonyms: Del(11Nmu2r-Sparc)2Anjm
Gene: Del(11Nmur2-Sparc)2Anjm  Location: unknown  Genetic Position: Chr11, Syntenic
Germline Transmission:  Earliest citation of germline transmission: J:155870
Parent Cell Line:  E14.1 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Allele Type:    Targeted (Null/knockout)
Mutations:    Deletion, Insertion
  Del(11Nmur2-Sparc)2Anjm involves 12 genes/genome features (Gm32165, Gm32012, Sparc ...) View all
Mutation detailsThis deletion was created by cre mediated recombination of loxP sites within Nmur2 (created by random insertion vector of loxP-Puro cassette) and Sparc (created by eliminating exon 6 and replacing it with a Neo-LoxP as well as inserting stop codons in all three reading-frames). The deletion spans a 0.5 Mb Mb interval between Nmur2 and Sparc and includes Glra1, G3bp1 and Atox1. (J:155870)
View phenotypes for all genotypes (concatenated display).
Disease models
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Del(11Nmur2-Sparc)2Anjm Mutation:  0 strains or lines available
Original:  J:155870 Barlow JL, et al., A p53-dependent mechanism underlies macrocytic anemia in a mouse model of human 5q- syndrome. Nat Med. 2010 Jan;16(1):59-66
All:  1 reference(s)

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.0
The Jackson Laboratory