Slc45a2^uw-6Btlr
Chemically induced Allele Detail

Summary

• Symbol: Slc45a2^uw-6Btlr
• Name: solute carrier family 45, member 2; underwhite 6 Bruce Beutler
• MGI ID: MGI:4420306
• Synonyms: Slc45a2^m6Btlr, zuckerkuss
• Gene: Slc45a2 Location: Chr15:11000807-11029319 bp, + strand Genetic Position: Chr15, 5.4 cM
• Alliance: Slc45a2^uw-6Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: This mutation, discovered among G3 progeny of an ENU treated mouse, comprises a G to T transversion at nucleotide position 25214 (Genbank genomic region NC_000081 for linear genomic DNA sequence of Slc45a2) that disrupts the donor splice site of intron 6. It is predicted to result in production of a protein truncated near the end of the eighth (of 12) transmembrane domain. (J:156310)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Slc45a2 Mutation: 55 strains or lines available

References

• Original: J:156310 Neppl C, et al., Zuckerkuss is an allele of Slc45a2 and displays pigmentation defects. MGI Direct Data Submission. 2010
• All: 1 reference(s)