Nfil3^tm2Look
Targeted Allele Detail

Summary

• Symbol: Nfil3^tm2Look
• Name: nuclear factor, interleukin 3, regulated; targeted mutation 2, A Thomas Look
• MGI ID: MGI:4418330
• Gene: Nfil3 Location: Chr13:53121245-53135109 bp, - strand Genetic Position: Chr13, 27.68 cM
• Alliance: Nfil3^tm2Look page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:155677
• Parent Cell Line: RW-4 (ES Cell)
• Strain of Origin: 129X1/SvJ

Mutation description

Allele Type: Targeted (Null/knockout, Reporter) Mutations: Insertion, Intragenic deletion Mutation details: A 1.7 kb fragment including exon 2 was replaced with an IRES- beta-galactosidase gene and a neomycin-resistance gene by homologues recombination. (J:155677)

Generation of the Nfil3^tm2Look allele

Expression

In Mice Carrying this Mutation:

18 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nfil3 Mutation: 31 strains or lines available

References

• Original: J:155677 Kamizono S, et al., Nfil3/E4bp4 is required for the development and maturation of NK cells in vivo. J Exp Med. 2009 Dec 21;206(13):2977-86
• All: 1 reference(s)