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Nfil3tm2Look
Targeted Allele Detail
Nomenclature
Symbol: Nfil3tm2Look
Name: nuclear factor, interleukin 3, regulated; targeted mutation 2, A Thomas Look
MGI ID: MGI:4418330
Gene: Nfil3  Location: Chr13:52967209-52981073 bp, - strand  Genetic Position: Chr13, 27.68 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:155677
Parent Cell Line:  RW-4 (ES Cell)
Strain of Origin:  129X1/SvJ
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA 1.7 kb fragment including exon 2 was replaced with an IRES- beta-galactosidase gene and a neomycin-resistance gene by homologues recombination. (J:155677)
Generation of the Nfil3tm2Look allele
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 18 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nfil3 Mutation:  5 strains or lines available
References
Original:  J:155677 Kamizono S, et al., Nfil3/E4bp4 is required for the development and maturation of NK cells in vivo. J Exp Med. 2009 Dec 21;206(13):2977-86
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/11/2020
MGI 6.14
The Jackson Laboratory