Mir206^tm1Eno
Targeted Allele Detail

Summary

• Symbol: Mir206^tm1Eno
• Name: microRNA 206; targeted mutation 1, Eric N Olson
• MGI ID: MGI:4418173
• Gene: Mir206 Location: Chr1:20749234-20749306 bp, + strand Genetic Position: Chr1, 6.41 cM
• Alliance: Mir206^tm1Eno page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:155806
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S/SvEv

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• Mutation details: The entire sequence was replaced with a neomycin cassette flanked by loxP sites. Northern blot analysis demonstrated absence of expression. (J:155806)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mir206 Mutation: 3 strains or lines available

References

• Original: J:155806 Williams AH, et al., MicroRNA-206 delays ALS progression and promotes regeneration of neuromuscular synapses in mice. Science. 2009 Dec 11;326(5959):1549-54
• All: 10 reference(s)