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Prkcitm1.1Kido
Targeted Allele Detail
Nomenclature
Symbol: Prkcitm1.1Kido
Name: protein kinase C, iota; targeted mutation 1.1, Yoshiaki Kido
MGI ID: MGI:4417855
Synonyms: aPKClambdadeleted
Gene: Prkci  Location: Chr3:30995742-31052740 bp, + strand  Genetic Position: Chr3, 14.65 cM
Focal segmental glomerulosclerosis in Prkcitm1Kido/Prkcitm1.1Kido Tg(Nphs1-cre)33Mska/0 mice

Show the 2 phenotype image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:154910
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    Exon 5 has been deleted. (J:154910)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 11 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Prkci Mutation:  54 strains or lines available
References
Original:  J:154910 Sugiyama Y, et al., A cell polarity protein aPKClambda is required for eye lens formation and growth. Dev Biol. 2009 Dec 15;336(2):246-56
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
10/01/2019
MGI 6.14
The Jackson Laboratory