Runx1^tm1.1Glac
Targeted Allele Detail

Summary

• Symbol: Runx1^tm1.1Glac
• Name: runt related transcription factor 1; targeted mutation 1.1, Georges Lacaud
• MGI ID: MGI:4417838
• Synonyms: distal^-
• Gene: Runx1 Location: Chr16:92398354-92622962 bp, - strand Genetic Position: Chr16, 53.7 cM
• Alliance: Runx1^tm1.1Glac page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:155698
• Parent Cell Line: BK4 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The coding region of exon 2 was replaced with GFP. A floxed neo cassette used for selection purposes was removed by cre mediated recombination. (J:155698)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Runx1 Mutation: 35 strains or lines available

Notes

ES cell = Ainv18, a tet-on inducible ES cell line made in BK4 ES cells.

References

• Original: J:155698 Sroczynska P, et al., The differential activities of Runx1 promoters define milestones during embryonic hematopoiesis. Blood. 2009 Dec 17;114(26):5279-89
• All: 2 reference(s)