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Nkapltm1(KOMP)Vlcg
Targeted Allele Detail
Nomenclature
Symbol: Nkapltm1(KOMP)Vlcg
Name: NFKB activating protein-like; targeted mutation 1, Velocigene
MGI ID: MGI:4415546
Gene: Nkapl  Location: Chr13:21467047-21468501 bp, - strand  Genetic Position: Chr13, 7.81 cM, cytoband A3.1
Mutation
origin
Mutant Cell Lines:  12856A-B1, 12856A-D12
Germline Transmission:  Earliest citation of germline transmission: J:204812
Parent Cell Line:  VGB6 (ES Cell)
Strain of Origin:  C57BL/6NTac
Project Collection: KOMP-Regeneron
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion     Vector: ZEN-Ub1
 
Mutation detailsThe insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 1191bp between positions 21559117-21560307 of Chromosome 13 (Genome Build37). Western blot analysis confirmed the absence of protein expression in the testis. (J:136110, J:229252)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 2 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 2 lines available
Carrying any Nkapl Mutation:  12 strains or lines available
References
Original:  J:136110 Velocigene, Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals). MGI Direct Data Submission. 2008;
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
12/03/2019
MGI 6.14
The Jackson Laboratory