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Tg(Ela-KRAS*G12D)9Eps
Transgene Detail
Nomenclature
Symbol: Tg(Ela-KRAS*G12D)9Eps
Name: transgene insertion 9, Eric P Sandgren
MGI ID: MGI:4414765
Synonyms: EL-KRAS, TgN(Ela1KRASG12D)9EPS
Transgene: Tg(Ela-KRAS*G12D)9Eps  Location: unknown  Genetic Position: ChrY, Syntenic
Transgene
origin
Strain of Origin:  FVB
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(Ela-KRAS*G12D)9Eps expresses 1 gene
 
Mutation detailsA genomic clone encoding human Kras-G12D, exons 1-4 was expressed in pancreatic ductal epithelial cells under the control of the 200-bp Ela enhancer/promoter. (J:83055)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:83055 Grippo PJ, et al., Preinvasive pancreatic neoplasia of ductal phenotype induced by acinar cell targeting of mutant kras in transgenic mice. Cancer Res. 2003 May 1;63(9):2016-9
All:  10 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/15/2020
MGI 6.15
The Jackson Laboratory