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Myg1tm1Mphi
Targeted Allele Detail
Nomenclature
Symbol: Myg1tm1Mphi
Name: melanocyte proliferating gene 1; targeted mutation 1, Mari-Anne Philips
MGI ID: MGI:4414758
Gene: Myg1  Location: Chr15:102331709-102338139 bp, + strand  Genetic Position: Chr15, 57.49 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:154911
Parent Cell Line:  W4 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA Lac-Z neo cassette replaced a 6.1 kb region immediately following the promoter region and including all 7 exons of the gene. In situ hybridization analysis confirmed the absence of mRNA expression in homozygous embryos. (J:154911)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Myg1 Mutation:  4 strains or lines available
References
Original:  J:154911 Philips MA, et al., Myg1-deficient mice display alterations in stress-induced responses and reduction of sex-dependent behavioural differences. Behav Brain Res. 2010 Feb 11;207(1):182-95
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
12/03/2019
MGI 6.14
The Jackson Laboratory