Ret^tm1.1Ddg
Targeted Allele Detail

Summary

• Symbol: Ret^tm1.1Ddg
• Name: ret proto-oncogene; targeted mutation 1.1, David D Ginty
• MGI ID: MGI:4413351
• Synonyms: Ret (V805A)
• Gene: Ret Location: Chr6:118128706-118174679 bp, - strand Genetic Position: Chr6, 55.86 cM, cytoband E3-F1
• Alliance: Ret^tm1.1Ddg page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:154926
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 14 and 15 and an FRT-flanked neomycin resistance gene cassette were flanked by loxP sites. The floxed exons and neo cassette were removed through subsequent cre-mediated recombination. (J:154926)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ret Mutation: 53 strains or lines available

References

• Original: J:154926 Mandai K, et al., LIG family receptor tyrosine kinase-associated proteins modulate growth factor signals during neural development. Neuron. 2009 Sep 10;63(5):614-27
• All: 3 reference(s)