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Pla2g10tm1Kiku
Targeted Allele Detail
Nomenclature
Symbol: Pla2g10tm1Kiku
Name: phospholipase A2, group X; targeted mutation 1, Kiyotaka Kugiyama
MGI ID: MGI:4412409
Synonyms: Pla2g10-, sPLA2-X-
Gene: Pla2g10  Location: Chr16:13715057-13730983 bp, - strand  Genetic Position: Chr16, 9.5 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:155082
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExons 1 and 2 were replaced with a neo cassette. The absence of transcript expression was confirmed by RT-PCR blot analysis on stomach and colon extracts. (J:155082)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 2 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pla2g10 Mutation:  33 strains or lines available
References
Original:  J:155082 Fujioka D, et al., Reduction in myocardial ischemia/reperfusion injury in group X secretory phospholipase A2-deficient mice. Circulation. 2008 Jun 10;117(23):2977-85
All:  9 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/10/2019
MGI 6.14
The Jackson Laboratory