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Zfp24hmcns
Spontaneous Allele Detail
Nomenclature
Symbol: Zfp24hmcns
Name: zinc finger protein 24; hypomyelinated central nervous system
MGI ID: MGI:4412036
Gene: Zfp24  Location: Chr18:24142759-24153867 bp, - strand  Genetic Position: Chr18, 12.55 cM, cytoband B1
Mutation
origin
Strain of Origin:  C3H/HeJ
Mutation
description
Allele Type:    Spontaneous
Mutation:    Insertion
 
Mutation detailsA spontaneous mutation with an A insertion in a stretch of four As, coding nucleotides 586-589, resulting in a frame-shift and premature stop codon, eliminating 155 amino acids including the zinc finger domain. (J:156938)
Inheritance:    Recessive
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 3 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Zfp24 Mutation:  20 strains or lines available
References
Original:  J:156938 Howng SY, et al., ZFP191 is required by oligodendrocytes for CNS myelination. Genes Dev. 2010 Feb 1;24(3):301-11
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/16/2021
MGI 6.17
The Jackson Laboratory