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Eedtm1Sho
Targeted Allele Detail
Summary
Symbol: Eedtm1Sho
Name: embryonic ectoderm development; targeted mutation 1, Stuart Orkin
MGI ID: MGI:4410540
Gene: Eed  Location: Chr7:89603862-89630184 bp, - strand  Genetic Position: Chr7, 50.42 cM
Alliance: Eedtm1Sho page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:154730
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S1/Sv
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA targeting vector was designed to insert a loxP site upstream of exon 3, and an frt-flanked neomycin resistance (neo) cassette was inserted between exons 6 and 7 followed immediately by a second loxP site. (J:154730, J:182226, J:205522)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Eed Mutation:  116 strains or lines available
References
Original:  J:154730 Yu M, et al., Insights into GATA-1-mediated gene activation versus repression via genome-wide chromatin occupancy analysis. Mol Cell. 2009 Nov 25;36(4):682-95
All:  42 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory