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Fzr1tm1.2Stge
Targeted Allele Detail
Nomenclature
Symbol: Fzr1tm1.2Stge
Name: fizzy and cell division cycle 20 related 1; targeted mutation 1.2, Stephen Geley
MGI ID: MGI:4410513
Gene: Fzr1  Location: Chr10:81366222-81378516 bp, - strand  Genetic Position: Chr10, 39.72 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:154779
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsCre mediated recombination of Fzr1tm1.1Stge removed exons 2 through 8. (J:154779)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Fzr1 Mutation:  34 strains or lines available
References
Original:  J:154779 Sigl R, et al., Loss of the mammalian APC/C activator FZR1 shortens G1 and lengthens S phase but has little effect on exit from mitosis. J Cell Sci. 2009 Nov 15;122(Pt 22):4208-17
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/05/2018
MGI 6.12
The Jackson Laboratory