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Ercc3tm1.1Gima
Targeted Allele Detail
Nomenclature
Symbol: Ercc3tm1.1Gima
Name: excision repair cross-complementing rodent repair deficiency, complementation group 3; targeted mutation 1.1, Giuseppina Giglia-Mari
MGI ID: MGI:4410296
Synonyms: Xpby, XpbYFP
Gene: Ercc3  Location: Chr18:32240304-32270151 bp, + strand  Genetic Position: Chr18, 17.97 cM, cytoband B3
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:154596
Parent Cell Line:  IB10/E14IB10 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion
 
Mutation detailsA cassette containing YFP, six histidine tags, a single hemagglutinin tag, and floxed neo cassette replaced the sequence between exon 15 and the poly adenylation sequence creating a fusion protein. Transient cre expression removes the neo cassette. (J:154596)
Generation of the Ercc3tm1.1Gima allele
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ercc3 Mutation:  24 strains or lines available
References
Original:  J:154596 Giglia-Mari G, et al., Differentiation driven changes in the dynamic organization of Basal transcription initiation. PLoS Biol. 2009 Oct;7(10):e1000220
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/10/2019
MGI 6.14
The Jackson Laboratory