Ercc3^tm1.1Gima
Targeted Allele Detail

Summary

• Symbol: Ercc3^tm1.1Gima
• Name: excision repair cross-complementing rodent repair deficiency, complementation group 3; targeted mutation 1.1, Giuseppina Giglia-Mari
• MGI ID: MGI:4410296
• Synonyms: Xpb^y, Xpb^YFP
• Gene: Ercc3 Location: Chr18:32373357-32403206 bp, + strand Genetic Position: Chr18, 17.97 cM, cytoband B3
• Alliance: Ercc3^tm1.1Gima page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:154596
• Parent Cell Line: IB10/E14IB10 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

Allele Type: Targeted (Null/knockout, Reporter) Mutation: Insertion Mutation details: A cassette containing YFP, six histidine tags, a single hemagglutinin tag, and floxed neo cassette replaced the sequence between exon 15 and the poly adenylation sequence creating a fusion protein. Transient cre expression removes the neo cassette. (J:154596)

Generation of the Ercc3^tm1.1Gima allele

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ercc3 Mutation: 31 strains or lines available

References

• Original: J:154596 Giglia-Mari G, et al., Differentiation driven changes in the dynamic organization of Basal transcription initiation. PLoS Biol. 2009 Oct;7(10):e1000220
• All: 3 reference(s)