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Targeted Allele Detail
Symbol: Ercc3tm1.1Gima
Name: excision repair cross-complementing rodent repair deficiency, complementation group 3; targeted mutation 1.1, Giuseppina Giglia-Mari
MGI ID: MGI:4410296
Synonyms: Xpby, XpbYFP
Gene: Ercc3  Location: Chr18:32240304-32270151 bp, + strand  Genetic Position: Chr18, 17.97 cM, cytoband B3
Germline Transmission:  Earliest citation of germline transmission: J:154596
Parent Cell Line:  IB10/E14IB10 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion
Mutation detailsA cassette containing YFP, six histidine tags, a single hemagglutinin tag, and floxed neo cassette replaced the sequence between exon 15 and the poly adenylation sequence creating a fusion protein. Transient cre expression removes the neo cassette. (J:154596)
Generation of the Ercc3tm1.1Gima allele
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ercc3 Mutation:  24 strains or lines available
Original:  J:154596 Giglia-Mari G, et al., Differentiation driven changes in the dynamic organization of Basal transcription initiation. PLoS Biol. 2009 Oct;7(10):e1000220
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory