Tg(tetO-Spdef)1Jaw
Transgene Detail

Summary

• Symbol: Tg(tetO-Spdef)1Jaw
• Name: transgene insertion 1, Jeffrey A Whitsett
• MGI ID: MGI:4399759
• Synonyms: TRE2-Spdef
• Transgene: Tg(tetO-Spdef)1Jaw Location: unknown
• Alliance: Tg(tetO-Spdef)1Jaw page

Absence of proliferation during goblet cell hyperplasia in Tg(Scgb1a1-rtTA)1Jaw/0 Tg(tetO-Spdef)1Jaw/0 mice

Show the 1 phenotype image(s) involving this allele.

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Inducible, Inserted expressed sequence)
• Inducer: doxycycline/tetracycline
• Mutation: Insertion
• Mutation details: The tetracycline response element 2 was used to drive the inducible, lung-specific expression of the mouse gene. Two lines were created (no line names given). (J:121284)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:121284 Park KS, et al., SPDEF regulates goblet cell hyperplasia in the airway epithelium. J Clin Invest. 2007 Apr;117(4):978-88
• All: 9 reference(s)