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Targeted Allele Detail
Symbol: S1pr5tm1Jch
Name: sphingosine-1-phosphate receptor 5; targeted mutation 1, Jerold Chun
MGI ID: MGI:4368002
Synonyms: S1P5-
Gene: S1pr5  Location: Chr9:21242917-21248443 bp, - strand  Genetic Position: Chr9, 7.75 cM, cytoband A4
Germline Transmission:  Earliest citation of germline transmission: J:154069
Parent Cell Line:  E14TG2a (ES Cell)
Strain of Origin:  129P2/OlaHsd
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
Mutation detailsCoding sequence for all but the first seven amino acid was replaced with a DsRed gene and a neo cassette. The absence of transcript expression was confirmed by RT-PCR analysis on spinal cord extracts. (J:154069)
Generation of the S1pr5tm1Jch allele
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any S1pr5 Mutation:  15 strains or lines available
Original:  J:154069 Jenne CN, et al., T-bet-dependent S1P5 expression in NK cells promotes egress from lymph nodes and bone marrow. J Exp Med. 2009 Oct 26;206(11):2469-81
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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MGI 6.14
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