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S1pr5tm1Jch
Targeted Allele Detail
Nomenclature
Symbol: S1pr5tm1Jch
Name: sphingosine-1-phosphate receptor 5; targeted mutation 1, Jerold Chun
MGI ID: MGI:4368002
Synonyms: S1P5-
Gene: S1pr5  Location: Chr9:21242917-21248443 bp, - strand  Genetic Position: Chr9, 7.75 cM, cytoband A4
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:154069
Parent Cell Line:  E14TG2a (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsCoding sequence for all but the first seven amino acid was replaced with a DsRed gene and a neo cassette. The absence of transcript expression was confirmed by RT-PCR analysis on spinal cord extracts. (J:154069)
Generation of the S1pr5tm1Jch allele
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any S1pr5 Mutation:  15 strains or lines available
References
Original:  J:154069 Jenne CN, et al., T-bet-dependent S1P5 expression in NK cells promotes egress from lymph nodes and bone marrow. J Exp Med. 2009 Oct 26;206(11):2469-81
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/10/2019
MGI 6.14
The Jackson Laboratory