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Cebpbtm3Nerl
Targeted Allele Detail
Nomenclature
Symbol: Cebpbtm3Nerl
Name: CCAAT/enhancer binding protein (C/EBP), beta; targeted mutation 3, Claus Nerlov
MGI ID: MGI:4366861
Synonyms: betadeltacre
Gene: Cebpb  Location: Chr2:167688915-167690418 bp, + strand  Genetic Position: Chr2, 87.58 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:153686
Parent Cell Line:  E14.1 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe cAMP response elements in the promoter region were replaced with 5 binding sites for the artificial ZFHD transcription factor. (J:153686)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cebpb Mutation:  12 strains or lines available
References
Original:  J:153686 Ruffell D, et al., A CREB-C/EBPbeta cascade induces M2 macrophage-specific gene expression and promotes muscle injury repair. Proc Natl Acad Sci U S A. 2009 Oct 13;106(41):17475-80
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/17/2017
MGI 6.10
The Jackson Laboratory