Atp7a^Mo-3Btlr
Chemically induced Allele Detail

Summary

• Symbol: Atp7a^Mo-3Btlr
• Name: ATPase, Cu++ transporting, alpha polypeptide; mottled 3 Bruce Beutler
• MGI ID: MGI:4366761
• Synonyms: Atp7a^brown, Brown
• Gene: Atp7a Location: ChrX:105070882-105168532 bp, + strand Genetic Position: ChrX, 47.36 cM
• Alliance: Atp7a^Mo-3Btlr page

Coat color phenotypes of mutants carrying the Atp7a^Mo-Btlr, Atp7a^Mo-2Btlr, or Atp7a^Mo-3Btlr allele

Show the 2 phenotype image(s) involving this allele.

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: This mutation comprises a T to C transition at nucleotide position 1570 of the cDNA, in the fifth of the gene's 23 exons. It results in replacement of isoleucine by threonine at amino acid 483 of the protein (I483T). (J:153280, J:188598)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Atp7a Mutation: 69 strains or lines available

References

• Original: J:153280 Siggs OM, et al., Record for "Brown", updated October 15, 2009. MGI Direct Data Submission. 2009
• All: 2 reference(s)