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Gt(ROSA)26Sortm6Dym
Targeted Allele Detail
Nomenclature
Symbol: Gt(ROSA)26Sortm6Dym
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 6, Susan Dymecki
MGI ID: MGI:4366498
Synonyms: mch/lox/GFP, RC::Epe
Gene: Gt(ROSA)26Sor  Location: Chr6:113067428-113077333 bp, - strand  Genetic Position: Chr6, 52.73 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:153743
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsThe locus was modified to contain a floxed mCherry coding region followed by a GFP coding region. Cre mediated expression is necessary to achieve GFP expression. Expression of mCherry and GFP is mutually exclusive. (J:153473)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gt(ROSA)26Sor Mutation:  287 strains or lines available
References
Original:  J:153743 Purcell P, et al., Temporomandibular joint formation requires two distinct hedgehog-dependent steps. Proc Natl Acad Sci U S A. 2009 Oct 27;106(43):18297-302
All:  8 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory