Ptpn11tm1.2Wbm
Targeted Allele Detail
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Symbol: |
Ptpn11tm1.2Wbm |
Name: |
protein tyrosine phosphatase, non-receptor type 11; targeted mutation 1.2, Walter Birchmeier |
MGI ID: |
MGI:4365540 |
Synonyms: |
Ptpn11tm1.2Cbm, Shp2delta |
Gene: |
Ptpn11 Location: Chr5:121268596-121329460 bp, - strand Genetic Position: Chr5, 61.72 cM, cytoband F
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Alliance: |
Ptpn11tm1.2Wbm page
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Germline Transmission: |
Earliest citation of germline transmission:
J:153219
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Parent Cell Line: |
E14.1 (ES Cell)
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Strain of Origin: |
129P2/OlaHsd
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Allele Type: |
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Targeted (Null/knockout) |
Mutations: |
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Insertion, Intragenic deletion
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Germ line, cre mediated recombination removed exon 3 and 4. (J:153219)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Ptpn11 Mutation: |
43 strains or lines available
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Original: |
J:153219 Grossmann KS, et al., The tyrosine phosphatase Shp2 (PTPN11) directs Neuregulin-1/ErbB signaling throughout Schwann cell development. Proc Natl Acad Sci U S A. 2009 Sep 29;106(39):16704-9 |
All: |
1 reference(s) |
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