Nkx3-1^tm3(cre)Mms
Targeted Allele Detail

Summary

• Symbol: Nkx3-1^tm3(cre)Mms
• Name: NK3 homeobox 1; targeted mutation 3, Michael M Shen
• MGI ID: MGI:4361334
• Synonyms: Nkx3.1^Cre, NKX3.1-Cre
• Gene: Nkx3-1 Location: Chr14:69428141-69432107 bp, + strand Genetic Position: Chr14, 36.02 cM
• Alliance: Nkx3-1^tm3(cre)Mms page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:119911
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Recombinase)
• Mutation: Insertion
• Nkx3-1^tm3(cre)Mms expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Nkx3-1 (MGI:97352)

• Cre was knocked into the locus, no details were provided. (J:119911)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Nkx3-1 (mouse) Summary of all recombinase alleles driven by Nkx3-1. Alliance mouse Nkx3-1 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Nkx3-1 Mutation: 39 strains or lines available

References

• Original: J:119911 Lin Y, et al., Fibroblast growth factor receptor 2 tyrosine kinase is required for prostatic morphogenesis and the acquisition of strict androgen dependency for adult tissue homeostasis. Development. 2007 Feb;134(4):723-34
• All: 17 reference(s)