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Targeted Allele Detail
Symbol: Nfil3tm1Look
Name: nuclear factor, interleukin 3, regulated; targeted mutation 1, A Thomas Look
MGI ID: MGI:4361260
Synonyms: Nfil3-
Gene: Nfil3  Location: Chr13:52967209-52981073 bp, - strand  Genetic Position: Chr13, 27.68 cM
Germline Transmission:  Earliest citation of germline transmission: J:153064
Parent Cell Line:  RW-4 (ES Cell)
Strain of Origin:  129X1/SvJ
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsA 2.2 kb fragment including exon 2 was replaced with a neomycin cassette by homologous recombination. The absence of transcript expression was confirmed by RT-PCR on hepatic extracts. (J:153064, J:155677)
Generation of the Nfil3tm1Look allele
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nfil3 Mutation:  12 strains or lines available
Original:  J:153064 Le Martelot G, et al., REV-ERBalpha participates in circadian SREBP signaling and bile acid homeostasis. PLoS Biol. 2009 Sep;7(9):e1000181
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.10
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