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Nfil3tm1Look
Targeted Allele Detail
Nomenclature
Symbol: Nfil3tm1Look
Name: nuclear factor, interleukin 3, regulated; targeted mutation 1, A Thomas Look
MGI ID: MGI:4361260
Synonyms: Nfil3-
Gene: Nfil3  Location: Chr13:52967209-52981073 bp, - strand  Genetic Position: Chr13, 27.68 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:153064
Parent Cell Line:  RW-4 (ES Cell)
Strain of Origin:  129X1/SvJ
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA 2.2 kb fragment including exon 2 was replaced with a neomycin cassette by homologous recombination. The absence of transcript expression was confirmed by RT-PCR on hepatic extracts. (J:153064, J:155677)
Generation of the Nfil3tm1Look allele
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nfil3 Mutation:  12 strains or lines available
References
Original:  J:153064 Le Martelot G, et al., REV-ERBalpha participates in circadian SREBP signaling and bile acid homeostasis. PLoS Biol. 2009 Sep;7(9):e1000181
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/11/2017
MGI 6.10
The Jackson Laboratory