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Hunktm1Lach
Targeted Allele Detail
Nomenclature
Symbol: Hunktm1Lach
Name: hormonally upregulated Neu-associated kinase; targeted mutation 1, Lewis A Chodosh
MGI ID: MGI:4361146
Gene: Hunk  Location: Chr16:90386397-90499553 bp, + strand  Genetic Position: Chr16, 51.71 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:153075
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsA 1.1 kb genomic fragment including the putative promoter and exon 1 was replaced with a floxed pgk-neo cassette via homologous recombination. (J:153075)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hunk Mutation:  22 strains or lines available
References
Original:  J:153075 Wertheim GB, et al., The Snf1-related kinase, Hunk, is essential for mammary tumor metastasis. Proc Natl Acad Sci U S A. 2009 Sep 15;106(37):15855-60
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/20/2016
MGI 6.05
The Jackson Laboratory