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Nipal3tm1Pbfd
Targeted Allele Detail
Nomenclature
Symbol: Nipal3tm1Pbfd
Name: NIPA-like domain containing 3; targeted mutation 1, Peter Burfeind
MGI ID: MGI:4360699
Synonyms: Npal3-
Gene: Nipal3  Location: Chr4:135445420-135495038 bp, - strand  Genetic Position: Chr4, 67.64 cM, cytoband D3
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:152829
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExons 3 through 8 were replaced with a neo cassette. The absence of transcript expression was confirmed by northern blot analysis on brain extracts. (J:152829)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 1 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nipal3 Mutation:  31 strains or lines available
References
Original:  J:152829 Grzmil P, et al., Targeted disruption of the mouse Npal3 gene leads to deficits in behavior, increased IgE levels, and impaired lung function. Cytogenet Genome Res. 2009;125(3):186-200
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
03/14/2017
MGI 6.08
The Jackson Laboratory