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Ccr5tm2Blck
Targeted Allele Detail
Nomenclature
Symbol: Ccr5tm2Blck
Name: chemokine (C-C motif) receptor 5; targeted mutation 2, Bruno Luckow
MGI ID: MGI:4360353
Gene: Ccr5  Location: Chr9:124121543-124147699 bp, + strand  Genetic Position: Chr9, 75.05 cM, cytoband F
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:152815
Parent Cell Line:  E14.1 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion
    The coding region was replaced with DsRed2 and a floxed hygro cassette. (J:152815)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ccr5 Mutation:  4 strains or lines available
Notes
This allele was originally generated in ES cells containing Ccr2tm1Blck.

References
Original:  J:152815 Luckow B, et al., Microinjection of Cre recombinase protein into zygotes enables specific deletion of two eukaryotic selection cassettes and enhances the expression of a DsRed2 reporter gene in Ccr2/Ccr5 double-deficient mice. Genesis. 2009 Aug;47(8):545-58
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory