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Kif7tm1Lex
Targeted Allele Detail
Nomenclature
Symbol: Kif7tm1Lex
Name: kinesin family member 7; targeted mutation 1, Lexicon Genetics
MGI ID: MGI:4360052
Gene: Kif7  Location: Chr7:79698098-79715720 bp, - strand  Genetic Position: Chr7, 45.09 cM, cytoband D2
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:152551
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S/SvEvBrd
Project Collection: Lexicon
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExon 2 was replaced with a lacZ gene and neo cassette. This insertion deletes the ATG initiation codon and 109 amino acids. (J:152551)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 8 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 3 strains available      Cell Lines: 0 lines available
Carrying any Kif7 Mutation:  26 strains or lines available
Notes
See also, data as provided by Lexicon Genetics, Inc.
References
Original:  J:152551 Endoh-Yamagami S, et al., The mammalian Cos2 homolog Kif7 plays an essential role in modulating Hh signal transduction during development. Curr Biol. 2009 Aug 11;19(15):1320-6
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
06/23/2020
MGI 6.15
The Jackson Laboratory