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Targeted Allele Detail
Symbol: Ghrtm1.2Masp
Name: growth hormone receptor; targeted mutation 1.2, Mark A Sperling
MGI ID: MGI:4359895
Gene: Ghr  Location: Chr15:3317755-3583352 bp, - strand  Genetic Position: Chr15, 1.84 cM
Small body size of Ghrtm1.2Masp/Ghrtm1.2Masp mice

Show the 1 phenotype image(s) involving this allele.

Germline Transmission:  Earliest citation of germline transmission: J:152627
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    Germ line, cre mediated recombination removed exon 4. (J:152627)
Generation of the Ghrtm1.1Masp and Ghrtm1.2Masp alleles
View phenotypes and curated references for all genotypes (concatenated display).
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ghr Mutation:  1 strain or line available
Original:  J:152627 Fan Y, et al., Liver-specific deletion of the growth hormone receptor reveals essential role of growth hormone signaling in hepatic lipid metabolism. J Biol Chem. 2009 Jul 24;284(30):19937-44
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.15
The Jackson Laboratory