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Bcar3tm1Lern
Targeted Allele Detail
Nomenclature
Symbol: Bcar3tm1Lern
Name: breast cancer anti-estrogen resistance 3; targeted mutation 1, Adam Lerner
MGI ID: MGI:4359826
Synonyms: AND-34-
Gene: Bcar3  Location: Chr3:122294136-122530191 bp, + strand  Genetic Position: Chr3, 53.41 cM, cytoband G3
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:152504
Parent Cell Line:  TC1/TC-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExon 4 and most of exon 5 were replaced with a neo cassette. The absence of protein expression was confirmed by western blot analysis of splenic lymphocyte extracts. (J:152504)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Bcar3 Mutation:  45 strains or lines available
References
Original:  J:152504 Near RI, et al., Loss of AND-34/BCAR3 expression in mice results in rupture of the adult lens. Mol Vis. 2009;15:685-99
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/12/2017
MGI 6.10
The Jackson Laboratory