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Nceh1tm1Ishi
Targeted Allele Detail
Nomenclature
Symbol: Nceh1tm1Ishi
Name: neutral cholesterol ester hydrolase 1; targeted mutation 1, Shun Ishibashi
MGI ID: MGI:4359388
Gene: Nceh1  Location: Chr3:27182965-27284608 bp, + strand  Genetic Position: Chr3, 10.82 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:152385
Parent Cell Line:  JH1 (ES Cell)
Strain of Origin:  129S7/SvEvBrd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExon 4 was replaced with a neo cassette. The absence of protein expression was confirmed by western blot analysis on brain and kidney extract. (J:152385)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nceh1 Mutation:  16 strains or lines available
References
Original:  J:152385 Sekiya M, et al., Ablation of neutral cholesterol ester hydrolase 1 accelerates atherosclerosis. Cell Metab. 2009 Sep;10(3):219-28
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/05/2017
MGI 6.11
The Jackson Laboratory