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Pros1tm1.1Ansc
Targeted Allele Detail
Nomenclature
Symbol: Pros1tm1.1Ansc
Name: protein S (alpha); targeted mutation 1.1, Anne Angelillo-Scherrer
MGI ID: MGI:4359168
Synonyms: Pros-
Gene: Pros1  Location: Chr16:62854307-62929346 bp, + strand  Genetic Position: Chr16, 36.43 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:152423
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129/Sv
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsGerm line, cre mediated recombination removes exons 3 through 7. The decreased protein expression was confirmed by western blot analysis on plasma from heterozygous mice. (J:152423)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pros1 Mutation:  4 strains or lines available
References
Original:  J:152423 Saller F, et al., Generation and phenotypic analysis of protein S-deficient mice. Blood. 2009 Sep 10;114(11):2307-14
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
03/24/2015
MGI 5.21
The Jackson Laboratory