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Stk4tm1.1Wtao
Targeted Allele Detail
Summary
Symbol: Stk4tm1.1Wtao
Name: serine/threonine kinase 4; targeted mutation 1.1, Wufan Tao
MGI ID: MGI:4358199
Synonyms: Mst1fl
Gene: Stk4  Location: Chr2:163916033-163997444 bp, + strand  Genetic Position: Chr2, 84.6 cM, cytoband H3
Alliance: Stk4tm1.1Wtao page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:152323
Parent Cell Line:  W4 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsAn frt flanked neo cassette with a 3' loxP site was inserted upstream of exon 4 and an additional loxP site was inserted downstream of exon 4. The neo cassette was removed by germ line, flp mediated recombination leaving exon 4 floxed. (J:152323)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Stk4 Mutation:  72 strains or lines available
References
Original:  J:152323 Dong Y, et al., A cell-intrinsic role for Mst1 in regulating thymocyte egress. J Immunol. 2009 Sep 15;183(6):3865-72
All:  7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory