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Kif7tm1.2Hui
Targeted Allele Detail
Nomenclature
Symbol: Kif7tm1.2Hui
Name: kinesin family member 7; targeted mutation 1.2, Chi-chung Hui
MGI ID: MGI:4357956
Synonyms: Kif7del
Gene: Kif7  Location: Chr7:79698098-79715720 bp, - strand  Genetic Position: Chr7, 45.09 cM, cytoband D2
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:152259
Parent Cell Line:  W4 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsGerm line, cre mediated recombination was used to remove exons 2 through 4. The absence of protein expression was confirmed by western blot analysis on E10.5 embryo extracts. (J:152259)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 8 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Kif7 Mutation:  26 strains or lines available
References
Original:  J:152259 Cheung HO, et al., The kinesin protein Kif7 is a critical regulator of Gli transcription factors in mammalian hedgehog signaling. Sci Signal. 2009;2(76):ra29
All:  9 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
06/23/2020
MGI 6.15
The Jackson Laboratory