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Terf1tm1.1Blas
Targeted Allele Detail
Nomenclature
Symbol: Terf1tm1.1Blas
Name: telomeric repeat binding factor 1; targeted mutation 1.1, Maria A Blasco
MGI ID: MGI:4357772
Synonyms: TRF1flox
Gene: Terf1  Location: Chr1:15805646-15844052 bp, + strand  Genetic Position: Chr1, 4.88 cM, cytoband E3
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:152077
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Terf1 Mutation:  12 strains or lines available
References
Original:  J:152077 Martinez P, et al., Increased telomere fragility and fusions resulting from TRF1 deficiency lead to degenerative pathologies and increased cancer in mice. Genes Dev. 2009 Sep 1;23(17):2060-75
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory