About   Help   FAQ
Pfkmtm1Fbos
Targeted Allele Detail
Nomenclature
Symbol: Pfkmtm1Fbos
Name: phosphofructokinase, muscle; targeted mutation 1, Fatima Bosch
MGI ID: MGI:4356541
Gene: Pfkm  Location: Chr15:98092589-98132447 bp, + strand  Genetic Position: Chr15, 54.09 cM
Pfkmtm1Fbos/Pfkmtm1Fbos mice develop skeletal muscle glycogenosis and exercise intolerance

Show the 4 phenotype image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:152153
Parent Cell Line:  CMTI-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Phenotypes
Loading...
View phenotypes for all genotypes (concatenated display).
Disease models
Loading...
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pfkm Mutation:  2 strains or lines available
References
Original:  J:152153 Garcia M, et al., Phosphofructo-1-kinase deficiency leads to a severe cardiac and hematological disorder in addition to skeletal muscle glycogenosis. PLoS Genet. 2009 Aug;5(8):e1000615
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
07/23/2014
MGI 5.19
The Jackson Laboratory